Vasectomies about to be a thing of the past! The injectable contraceptive that FDA is approving

Male contraceptive options may become a lot more comfortable. An injectable contraceptive dubbed RISUG is winding its way through the FDA approval process and may be ready for rollout within a year.

RISUG, an acronym for reversible inhibition of sperm under guidance, is non-hormonal, minimally invasive, reversible, and effective for up to 10 years. According to, “it’s like having a vasectomy—without the permanent snip.”

Current male birth control methods are basically limited to abstinence, withdrawal, condoms, and vasectomies. Of the latter, the Mayo Clinic lists some of the risks:

“Side effects right after surgery can include bleeding or a blood clot inside the scrotum, infection of the surgery site, bruising, and blood in your semen… Delayed complications can include chronic pain, which can happen for 1% to 2% of people who have surgery, fluid buildup in the testicle, which can cause a dull ache that gets worse with ejaculation, and inflammation caused by leaking sperm (granuloma).”

“Although it might be possible to reverse your vasectomy, there’s no guarantee it will work. Reversal surgery is more complicated than vasectomy, can be expensive and is ineffective in some cases.” according to the Clinic.

“RISUG has been showing promising results for decades,” according to verywellhealth. “Current clinical studies show that the male birth control shot has been shown to be 99% effective—this is about the same rate as female hormonal birth control methods.

“As of 2019, RISUG was in the late stages of clinical testing in India and had been patented in India, China, and the United States.

“In the United States, Vasalgel, which is a contraceptive method based on RISUG, is the male birth control option furthest along in clinical trials and is closest to be the first new U.S. option marketed for men. Vasalgel is currently undergoing animal and safety trials, but human clinical trials have not yet started,” reported verywellhealth.

Vasalgel has been in development for a decade by The Parsemus Foundation and its social venture subsidiary Revolution Contraceptives, LLC, which have recently partnered with NEXT Life Sciences to continue the development of the Vasalgel male contraceptive. On its website, The Parsemus Foundation invites interested parties to sign up for updates regarding the development of Vasalgel.

“Over the last two decades RISUG has been drawing attention in the field of male contraception,” notes a 2014 study published in the Indian Journal of Medical Research. “It promises to sterile men for a period of up to 10-15 years. According to recent studies in animal models, it proves to be completely reversible. Practically, there are no better options available that can assure complete sterility and precise reversibility. Regardless of so much of information available, RISUG is still holding up for many reasons,” further noting:

“The burden of population control has been generally borne by women while men fall behind due to lack of efficient and acceptable contraceptive. Available methods are mostly dependent on permanent vasectomy and widely used condoms that are reluctantly accepted in men’s world. In early 80s Misro et al1 came with a revolutionary occlusive polymer which was claimed to sterile subjects by single injection of styrene maleic anhydride (SMA) dissolved in dimethyl sulphoxide (DMSO), in both vas deferens; it was named as RISUG.”

It appears that many men are impatient for the rollout of the radically new contraceptive choice.


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